/ Home
/ SUBMISSION

/ The BJOC
/ Diamond Open Access
/ Journal Statistics
/ Editorial Board
/ Community
/ Call for papers

/ Latest Articles
/ Most accessed
/ Thematic issues
/ Volumes
/ Authors

/ Alerts

/ TWITTER
/ LINKEDIN
/ Mastodon
/ RSS FEED

Empty search

Article Type

Publication Date Range

Search Tips

This search combines search strings from the content search (i.e. "Full Text", "Author", "Title", "Abstract", or "Keywords") with "Article Type" and "Publication Date Range" using the AND operator.

Search Examples

aromatic	the word “aromatic”
aromatic aldehyde	the word “aromatic” OR “aldehyde”
+aromatic +aldehyde	both words “aromatic” AND “aldehyde”
+aromatic -aldehyde	the word “aromatic” but NOT “aldehyde”
“aromatic aldehyde”	the exact phrase “aromatic aldehyde”
benz*	words which begin with “benz”, such as “benzene” or “benzyl”
benz*yl	words that begin with “benz” and end with “yl”, such as “benzyl” or “benzoyl”
benzyl~	words that are close to the word “benzyl”, such as “benzoyl” (i.e., fuzzy search)

BROWSE
Latest Articles
Most accessed
thematic issues
volumes
authors

BROWSE

Latest Articles Most Accessed Thematic Issues Volumes Authors

Author

1 article(s) from Perseghini, Mauro

Development of the titanium–TADDOLate-catalyzed asymmetric fluorination of β-ketoesters

Lukas Hintermann,
Mauro Perseghini and
Antonio Togni

Beilstein J. Org. Chem. 2011, 7, 1421–1435, doi:10.3762/bjoc.7.166

PDF

Graphical Abstract

Figure 1: Fluorinated substances of biomedical relevance.

Jump to Figure 1

Scheme 1: Enantioselective electrophilic fluorination catalyzed by TADDOLates K1, K2. TADDOL = α,α,α',α'-tetr...

Jump to Scheme 1

Scheme 2: Halogenation of β-ketocarbonyl compounds: Importance of enolization and the potential role of a met...

Jump to Scheme 2

Figure 2: Model substrates for catalytic fluorinations, with the degree of enolization determined by ¹H NMR m...

Jump to Figure 2

Figure 3: ¹H NMR (250 MHz) spectra of fluorination reaction mixtures diluted with CDCl₃ and filtered. a) Full...

Jump to Figure 3

Scheme 3: Qualitative ordering of catalytic activity of several Lewis acids in the fluorination 1→1-F.

Jump to Scheme 3

Scheme 4: Catalysis of the “neutral” fluorination of β-ketoesters with F–TEDA by Lewis acidic titanium comple...

Jump to Scheme 4

Figure 4: Structure of the chiral ansa-metallocene [(EBTHI)Ti(OTf)₂].

Jump to Figure 4

Figure 5: Electrophilic fluorinating reagents of the N–F-type. F–TEDA [27]; NFTh = 1-fluoro-4-hydroxy-1,4-diazoni...

Jump to Figure 5

Scheme 5: Synthesis of trifluoromethyl-substituted TADDOL ligands.

Jump to Scheme 5

Scheme 6: Correlation experiments for the assignment of absolute configuration to fluorination products 11-F, ...

Jump to Scheme 6

Scheme 7: Mechanistic scheme proposed, based on visual and spectroscopic observations. L = solvent, counterio...

Jump to Scheme 7

Figure 6: ¹H NMR spectra of a species of the type A, generated in CD₃CN solution from K1 by ionization in the...

Jump to Figure 6

Figure 7: Steric model explaining the face selectivity observed in the titanium–TADDOLate complex catalyzed f...

Jump to Figure 7

Figure 8: Excerpt from the X-ray structure of a catalyst/substrate complex [Ti(1-naphthyl-TADDOLato)(β-ketoen...

Jump to Figure 8

Album

Supp Info

Full Research Paper

Published 17 Oct 2011

Full text

Other Beilstein-Institut Open Science Activities

/ Help / Support & Contact / Alerts / Privacy Policy / Terms & Conditions / Impressum